The first phase includes the former Faculty of Humanities and Philosophy, the new Rectorate, the Sports Center, and the Utility Plant, all located in the hilly area bordering the western plateau.
The second phase comprises the former Faculties of Medicine and Pharmacy, together with two research centers, situated in the upper portion of the site.
The master plan for the first phase is organized around two orthogonal axes.
The first is defined by the Rectorate axis, which marks the principal entrance to the campus from the upper side—along Via dei Vestini—and incorporates a pedestrian route descending toward the lower part of the site.
The second axis is articulated by the three buildings of the former Faculty of Humanities: the comb-shaped departmental building, the linear teaching block, and the cylindrical auditorium.
These three elements are arranged around an elongated valley that rises eastward along the hillside, creating a visual corridor that links the historic hilltop core of Chieti Alta with the Pescara valley.
The focal point of this perspective is the cylindrical auditorium, positioned on the site’s flat terrace and shaded by a dense, regularly planted grove of trees.
The auditorium occupies a strategic junction within the overall composition, acting as both a visual and functional hinge between the principal spatial sequences. 
The buildings are generally oriented transversely to the contour lines, resting directly on the sloping terrain—without mediation—with the deliberate intention of generating new pathways and unexpected vistas across the surrounding hills and valleys.
The relationships among the various elements are articulated through a network of open spaces and pedestrian routes that connect—and occasionally intersect—the buildings, imparting  a distinctive typological character to the overall composition.

Key Spatial Elements

1. The open space bordered by the three buildings of the former Faculty of Humanities serves as the true campus field. At its lower end, it culminates in a small paved square facing the cylindrical auditorium, which forms the geometric center and principal collective space of the entire complex.
2. A linear axis, defined by the gallery walkway and stepped internal street, traverses the new Rectorate and establishes a direct connection with the auditorium.
3. An internal route ascends through the departmental building of the former Faculty of Humanities, leading to the open courtyard of the Utility Plant.

Located in the northern portion of the site, near Via dei Vestini, the CUS Sports Center is conceived as a large enclosed courtyard defined by exposed brick walls.
Within a compact and integrated system, it accommodates both the gymnasium and the outdoor tennis courts.
The elongated southern façade, embedded in the natural terrain, gradually emerges from the hillside. A pergola-covered rooftop walkway offers an exceptional vantage point over the playing fields and the new University buildings, reinforcing visual continuity across the campus.

The second phase began with the acquisition of an additional area to the east, closer to the historic city center. This expansion was conceived to accommodate the Degree Programme and Clinic of Dentistry, the permanent facilities of the former Faculty of Medicine, the Faculty of Pharmacy, and two major medical research centers.
Given the need for a substantial volumetric expansion that exceeded the parameters of the original campus concept, it was decided to concentrate the new buildings into a compact nucleus located in the eastern portion of the site, thereby ensuring efficient land use and functional integration. 
The proposed solution—aptly named the Cittadella della Scienza (Citadel of Science)—was primarily guided by the aim of establishing a strong architectural boundary along the site’s edge, visually distinguishing the new University buildings from the adjacent hospital complex.
At the same time, this design choice responds to specific functional requirements, highlighting the advantages of locating healthcare-related degree programs in close proximity to hospital facilities, thereby fostering integration among academic activities, clinical practice, and research.
The architectural approach of the Cittadella della Scienza establishes a distinct relationship with the terrain compared to the buildings constructed during the first phase. In this case, a substantial plinth functions as an "artificial ground" upon which the ordered ensemble of programme buildings is arranged.
This elevated datum redefines the site, taking the form of a large horizontal plaza and panoramic terrace, carved out by a system of patios corresponding to classrooms and laboratories, and also accomodating an underground parking facility. The trapezoidal base is geometrically aligned with the layout that organises the rest of the campus buildings. Along its southern edge, the platform terminates in alignment with the visual corridor defined by the departmental buildings of the former Faculty of Humanities.
The buildings on the terrace are organised in two rows of parallel volumes, connected by lower glazed elements. These linear structures are oriented transversely to the main slope of the site, allowing visual permeability between the hill and the valley. 
Aligned with the educational complex, the two medical research centers are positioned on the opposite side of the valley, their façades articulated by an alternating rhythm of slender towers and transparent volumes.
To reinforce the architectural unity of the campus—despite its marked typological variety—the construction was executed using a limited palette of materials, applied consistently across the different buildings.
The predominant material is exposed brickwork, executed as cladding walls over reinforced-concrete structural frames, using the typical double-wythe masonry bond. This treatment is particularly evident in the earliest buildings constructed: the former Faculty of Humanities, the Sports Center, the Rectorate, and the base platform of the Cittadella della Scienza.
Within this overall material strategy, certain architecturally significant elements—such as the Rectorate façade facing the valley or the cylindrical auditorium—are distinguished by the use of travertine cladding.